Antithrombin III deficiency

I had my first deep vein thrombosis and pulmonary embolism at 18 years old due to May-Thurner Syndrome. My symptoms were left lower abdomen pain and fainting. I was told multiple times it was a miracle I was alive due to the clot burden. I spent 12 days in the hospital and had a temporary…

I developed my first blood clot at 16 years old, a massive deep vein thrombosis (DVT) in my left leg, extending from the middle of my shin to my belly button. Unfortunately, this clot resulted in multiple pulmonary emboli (PE), both caused by oral contraceptives.   I developed another DVT at eight weeks pregnant, even…

In 1983, I began experiencing pain in my side, shortness of breath and coughing up blood. At the ER, I was diagnosed with pleurisy, which is inflammation of the tissues that line the lungs and chest cavity. I was only 17 years old. Two weeks later, I began having pain in my left groin and…

The Road to Diagnosis As far back as my teenage years, I had experienced chronic shortness of breath. This worsened in my twenties and thirties as new symptoms emerged, including occasional chest and arm pains and general exhaustion. Over the years I sought the opinions of countless doctors, leading to misdiagnosis after misdiagnosis, …

I was sitting outside enjoying the fresh air when my FitBit said my heart rate was up to 100. I just had surgery to put in a plate and screws for a broken tibia (shin bone). My mom was concerned that she saw signs of a blood clot in my leg. When she touched my…

Three years ago, I was starting a new school year with dozens of other school teachers in my district. About a week after going back to work, I noticed some changes in my health. I seemed more fatigued than usual, and I noticed my ankles were swollen. While walking my son around his new school…

Early in January 2017, my healthy 16-year-old son Christian began experiencing lower back pain that radiated down the back of both of his legs. He has a black belt in Karate, and we thought he hurt himself in class, as did our pediatrician. A few days later, and after taking over-the-counter medications with little relief,…

I always love to hear the stories of how people beat cancer and overcame diseases, but I never thought anything bad would happen to me. My name is Jenny, and I am a 17-year-old girl who lives in a small town in Iowa. In my high school, I am involved in many activities, including softball,…

I noticed I had a cough that would not go away in November 2007. I knew it wasn’t a cold, because I didn’t have any other symptoms of a cold.  I went to my doctor the next month, and she couldn’t identify a cause.  She suggested that I try allergy medication for a week, but…

Cassie Sheffield and her birth family were affected by blood clots, and discovered that the family has a genetic blood clotting disorder, Antithrombin (AT) III deficiency, that carries a high risk for blood clots.  Cassie not only developed multiple pulmonary emboli in her teenage years, she learned that her mother and two brothers had AT…