Thrombophilia Resources

What is Thrombophilia?

Thrombophilia (also known as hypercoagulability) is a predisposition to develop blood clots. It is also referred to as hypercoagulation state or hypercoagulability. You can either inherit or acquire your thrombophilia during your lifetime.

You can acquire or develop a thrombophilia from abnormalities of the blood, such as too many red blood cells (polycythemia), or too many platelets (thrombocytosis or thrombocythemia), placement of a mechanical heart valve, the development of abnormal proteins or antibodies, or diseases of the kidney or liver, or HIV infection.

Thrombophilia Resources

You can learn more about thrombophilia and its many forms, including risks and potential complications, current perspectives about testing and diagnosis, and an overview of potential treatment options and lifestyle adjustments that you and your physician may consider necessary, at the link below:

• Understanding Thrombophilia

You can read more information about specific thrombophilias through the links below:

• Antiphospholipid Syndrome Resources:
  • Antiphospholipid Syndrome
  • More about Antiphospholipid Syndrome (APS) Written by: Jan M. Pankey, M.D.
• Antithrombin Deficiency Resources:
  • Antithrombin Deficiency
  • Antithrombin Deficiency An In-Depth Guide for Patients and healthcare Providers By Dr. Stephan Moll
• Factor V Leiden Resources
  • Factor V Leiden
  • What is Factor V Leiden?
  • Factor V Leiden FAQs
• Homocysteine and MTHFR Mutation Resources
• Inherited Thrombophilias Comparison Chart
• May-Thurner Syndrome Resources
• Protein S Deficiency & Protein C Deficiency Resources
• Prothrombin G20210A (Factor II Mutation) Resources

Genetic Testing

Talk to your healthcare provider about any questions you might have about genetic testing, and get more information and guidance from a genetic counselor. You can search for a genetic counselors in your local community here: Find a Genetic Counselor

Additional Resources: 

• Family Testing for Blood Clot Disorders
• The Genetics of Thrombophilia by  Elizabeth Varga, M.S.

PEP Talk: Patients Educating Patients: Family Health History – Genetic Testing & VTE

Thrombophilia Testing for Clinical Management

Thrombophilia and Pregnancy