If I have had a blood clot, do I need to be tested for thrombophilia?

There is controversy about exactly who should be tested for thrombophilia, so the answer to this question depends on the specific situation. Most experts agree that the following persons with thrombosis should be tested for thrombophilia:

  • Younger individuals with a blood clot (age younger than 50 years)
  • Individuals with a spontaneous blood clot
  • Individuals with extensive blood clots or clots in an unusual location (for example, the veins of the brain or liver)
  • Individuals with a blood clot who have family members who have had a DVT or PE
  • Women who have had recurrent miscarriages or certain other pregnancy complications, such as babies with poor growth (fetal growth restriction), premature separation of the placenta from the uterus (placental abruption), preeclampsia (high blood pressure of pregnancy), or stillbirth

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