Key Findings from Recent Investigator-Initiated Multicenter Trials in Pediatric Venous Thromboembolism Treatment and Prevention

Venous thromboembolism (VTE) is increasingly being diagnosed in pediatric patients. In fact, VTE has become one of the most common complications of hospitalization in children. The consequences of VTE in childhood can be felt lifelong. Therefore, improving knowledge on pediatric VTE treatment and prevention is a public health priority that should engage patients, parents, pediatric and adult primary care providers, and subspecialists.

The Centers for Disease Control and Prevention and the National Blood Clot Alliance are partnering on a webinar, moderated by Dr. Julie Jaffray, to discuss key research findings around pediatric VTE. Dr. Neil Goldenberg and Dr. Anthony Sochet will discuss incidence of VTE in children, risk factors, and outcomes, as well as critical knowledge gaps in optimal treatment and prevention.

They will then summarize the design and findings of two recently published investigator-initiated clinical trials of VTE treatment (Kids-DOTT phase 3 multinational trial on duration of anticoagulation in patients younger than 21 years old with provoked VTE) and prevention (COVAC-TP, U.S. national phase 2 on pharmacological thromboprophylaxis in children hospitalized for COVID-19-related illness, including multisystem inflammatory syndrome in children).

Lastly, they will outline key questions for future research.

Learning Objectives:

• Describe the incidence, risk factors, and outcomes of VTE in children.
• Identify historical knowledge gaps in pediatric VTE treatment and prevention.
• Describe the latest evidence on the optimal duration of anticoagulation for the treatment of provoked VTE in patients younger than 21 years of age.
• Describe the safety of enoxaparin thromboprophylaxis in children hospitalized for COVID-19.

Register

This hour-long webinar, scheduled for 2 p.m. ET on March 23, is free and open to healthcare providers, pharmacists, and public health researchers who desire more information about venous thromboembolism. Advance registration is required, and the number of attendees is limited. For more information and to register, click here. Questions? Contact Cindy Sayers.