Information on Specific Thrombophilias

Factor V Leiden

Click on the Resource Below	PDF/Printable	Key Points
American Heart Association- Circulation Patient Page 2003	Yes	Understanding blood clotting; Factor V; Factor V Leiden; How Does One get FVL; Diagnosing FVL; Implications of FVL; Treatment of FVL; Implications for Women; Testing of family members; Minimizing risks
US. National Library of Medicine March 2004	Yes	What is factor V Leiden thrombophilia; How common? Genetics; Inheritance; Links to resources
Gene Clinics- NIH and University of Washington	Yes	Covers factor V Leiden thrombophilia; focus on genetics; genotype/phenotype correlations; reviews data about FVL and how it pertains to thrombotic risks; mention of other thrombophilias
Learning about Factor V Leiden Thrombophilia: The National Human Genome Research Institute	Print version available	What is factor V Leiden thrombophilia; What are the symptoms? How is it diagnosed? How is it treated? What do we know about the hereditary of FVL? Clinical research. Additional resources.

Prothrombin G20210A

Resource	PDF/Printable	Key Points
American Heart Association Circulation Patient Page 2004	Yes	Understanding blood clotting; Prothrombin/prothrombin mutation; How Does One get the prothrombin mutation; Diagnosing prothrombin mutations; Implications of the prothrombin mutation; Treatment of prothrombin mutation; Implications for Women; Testing of family members; Minimizing risks
GeneClinics- NIH and University of Washington	Print version available	Covers prothrombin G20210A thrombophilia with a focus on genetics; reviews data about prothrombin and how it increases the risk of blood clots; describes other risk factors for blood clots and how they interact with prothrombin

Protein C and Protein S Deficiency

Resource	PDF/Printable	Key Points
US Natl Library of Medicine; Medline Plus 8/18/03	Yes	Definition; Causes, Incidence, Risk Factors; Symptoms; Signs and tests; Prognosis; Treatments

Antithrombin III Deficiency

Resource	PDF/Printable	Key Points
Antithrombin Deficiency: An In-Depth Guide for Patient and Health Care Providers	Yes	What is Antithrombin and why is it important?; Inherited and acquired antithrombin deficiency; antithrombin deficiency in children, women, surgical patients; diagnosis; treatment; family testing; practical and key issues related to antithrombin deficiency.
Healthlink Medical College of Wisconsin 3/17/99	By highlighting only	Definition; Signs and Symptoms; Causes; Treatment
National Organization for Rare Disorders 2002	No. Can order full-text article	Synonyms; Disorder subdivisions; Brief description; related organizations
US Natl Library of Medicine; Medline Plus 2/2/02	Yes	Definition

Antiphospholipid antibodies (lupus anticoagulant, anticardiolipin antibodies

Resource	PDF/Printable	Key Points
Medicinenet, Inc	Printable	What is antiphospholipid syndrome; Testing; Causes; Treatment;
Lupus Foundation; Michelle Petri, M.D., M.P.H.; Assoc. Professor Johns Hopkins 1/3/01	By highlighting only	What are APA's; How common; Why important; How diagnosed; Treatment; Pregnancy;
American Heart Association Circulation Patient Page 2005 8/18/03	Printable	What are APA's; How common; Why important; How diagnosed; Treatment; Pregnancy;

Homocysteine (Elevated) MTHFR mutation(s)

Resource	PDF/Printable	Key Points
American Heart Association Circulation Patient Page 2005 8/18/03	Yes	Causes of elevated homocysteine; How homocysteine is measured; homocysteine and thrombosis; What are risks? Women’s health; Information on the MTHFR (methylenetetrahydrofolate reductase) mutation.